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Paper | Regular issue | Vol 29, No. 4, 1989, pp.691-706
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4821
Synthesis and Reactions of Isoquinolines IV. Reactions of 3-Chloroisoquinoline-4-carbaldehydes

Elmar Konz and Wolfgang Rüger*

*Entwicklungsgruppe Synthese und SBU Antiinfektiva, Allgemeine Pharma Forschung, Hoechst AG, Postfach 800320, D-65926 Frankfurt, Main 80, Germany

Abstract

3-Chloroisoquinoline-4-carbaldhydes 2 are versatile intermediates for various functional manipulations as e.g. oxidation or reduction of the formly group or nucleophilic substitution of the chloro substituent leading to products with interesting pharmacological properties.