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Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
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January 13, 2023
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Paper | Regular issue | Vol 29, No. 9, 1989, pp.1689-1694
Published online, 1st January, 1970■ Nortenuipine-2’β-N-oxide, a New Bisbenzylisoquinoline Alkaloid from Daphnandra dielsii
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4957
■ Nortenuipine-2’β-N-oxide, a New Bisbenzylisoquinoline Alkaloid from Daphnandra dielsii
Ahmed M. Galal, Colin, D. Critchett, I. Ralph C. Bick, Subramaniam Sotheeswaran, Cong-yuan Gao, Fu-tyan Lin, Francis K. Duah, Emil W. Fu, Lan K. Wong, and Paul L. Schiff, Jr.*
*Department of Pharmaceutal Science, School of Pharmacy, University of Pittsburgh, University of Pittsburgh, U.S.A.
Abstract
Repeated chromatography of the nonquaternary alkaloid fraction of an extract of the bark of Daphandra dielsii Perk. (Monimiaceae) over silica gel afforded the new bisbenzylisoquinoline alkaloid (-)-nortenuipine-2’β -N-oxide (1) which was characterized by a consideration of physicochemical data and reduction to (-)-nortenuipine. In addition, seven other bisbenzylisoquinoline alkaloids of known structure were isolated and identified.
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