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Paper | Regular issue | Vol 29, No. 9, 1989, pp.1729-1733
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5033
A Convenient One Pot Synthesis of 3-Thiosubstitutes Coumarins

Vinod Kumar Ahluwalia,* Mohamad Alauddin, Chandra Has Khanduri, and Vimal Deep Mehta

*Department of Chemistry, University of Delhi, Delhi-110 007, India

Abstract

Several 3-thiosubstituted coumarins (5) are prepared by the reaction of thioacetonitriles (2) with o-hydroxybenzaldehydes (3) in ethanol using catalytic amount of sodium hydroxide followed by acidic hydrolysis of intermediate imines (4).