Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 29, No. 9, 1989, pp.1773-1779
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5042
Addition of Arylzirconium Tributoxides to 17-Ketosteroids

Virendra Kumar* and Malcolm R. Bell

*Sterling Winthrop Pharmaceuticals Research Division, Rensselaer, New York, 12144, U.S.A.

Abstract

Reaction of 17-oxoandrost-2,4-dieno[2,3-d]isoxazole 3 with arylzirconium tributoxides gives the corresponding C-17 aryl carbinols. Arylzirconium tributoxides are selective nucleophiles towards readily enolizable 17-ketosteroids and are less basic than lithium and Grignard reagents.