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■ Woodfordins A, B, and C, Dimeric Hydrolyzable Tannins from Woodfordia fruticosa Flowers

Takashi Yoshida, Tong Chou, Aya Nitta, and Takuo Okuda*

*Faculty of Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima-naka, Okayama 700-8530, Japan

Abstract

Three new dimeric hydrolyzable tannins, woodfordins A, B, and C, along with six known hydrolyzable tannins including oenothein B, a dimer which exhibited remarkable host-mediated antitumor activity, were isolated from an Indonesian crude drug, “Sidowayah” [dried flowers of Woodfordia fruticosa (L.) Kurz (Lythraceae)]. The structures of new dimers were elucidated by chemical and spectral methods.