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Paper | Regular issue | Vol 31, No. 3, 1990, pp.485-492
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5204
Preparation of a New Chiral 5,6-Dihydropyridinium Synthon

Anna Diez, Huang Pé-Quiang, David S. Grierson, Henri-Philippe Husson, and Mario Rubiralta

*Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Av. de Joan XXIII, s/n, 08028 Barcelona, Spain

Abstract

A new chiral synthon, oxazolidinonepiperidine 7, is prepared from intermediate 5, derived from (S)-(-)-ethyl lactate, by chemoselective reduction of the piperideinone carbonyl group followed by oxazolidinone ring closure.