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Communication | Regular issue | Vol 31, No. 2, 1990, pp.211-214
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5256
Facile Synthesis of Tetrahydro-2-furylated Pyrimidines and Purines Using a New Catalyst of Cesium Chloride

Chun Ho Lee, Joong Young Kim, Wan Joo Kim, and Yong Hae Kim*

*Department of Chemistry, Korea Advanced Institute of Science and Technology, P. O. Box 150, Cheong-ryang, Seoul 130-650, Korea

Abstract

1-(Tetrahydro-2-furyl)pyrimidine and 9-(tetrahydro-2-furyl)purine derivatives were successfully synthesized in good yields by the reactions of trimethylsilylated pyrimidine and purine bases with 2-acetoxytetrahydrofuran using a new catalyst of cesium chloride in acetonitrile under mild conditions.