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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 31, No. 3, 1990, pp.419-422
Published online, 1st January, 1970■ Base-induced Condensation of Phenols Joined by Amides to Ketones: A Synthesis of Hydroxylated Isoquinolinones and Derivatives
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5296
■ Base-induced Condensation of Phenols Joined by Amides to Ketones: A Synthesis of Hydroxylated Isoquinolinones and Derivatives
Richard Friary,* John H. Schwerdt, Vera Seidl, and John G. Topliss
*Schering-Plough Research, Schering-Plough Corporation, 86 Orange Street, Bloomfield, New Jersey 07003, U.S.A.
Abstract
Pottassium carbonate in methanol saponified the acetate ester groups of certain meta-acetoxylated α-benzamido ketones and cyclized the resulting phenols in situ to give a series of hydroxylated isoquinolinones and derivatives.
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