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Communication | Special issue | Vol 30, No. 2, 1990, pp.795-798
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S108
Lignans and Sesquiterpenoids asa PAF Antagonists

Satoshi Iwakami, Yutaka Ebizuka, and Ushio Sankawa*

*Faculty of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Abstract

Some lignans and sesquiterpenes were found to have potent PAF antagonist activities. In particular, 6-O-angeloyl- and 6-O-senecioylplenolins (18,19) are the most potent and specific PAF antagonists found in this study.