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Paper | Regular issue | Vol 31, No. 9, 1990, pp.1669-1685
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5488
Synthesis and Antiviral Activity of 1,2,3-Triazole and 8-Azapurine Derivatives Bearing Acyclic Sugars

Masataka Yokoyama,* Eiko Nakao, Keiko Sujino, Satoshi Watanabe, and Hideo Togo

*Department of Chemistry, Faculty of Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan

Abstract

A variety of 1,2,3-triazole and 8-azapurine derivatives bearing acyclic sugar moieties were synthesized by the reaction of acyclic sugar azides with α-cyanoacetamide, norbornadiene, and acetylene derivatives, respectively. Antiviral tests of these compounds are also described.