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Paper | Regular issue | Vol 32, No. 1, 1991, pp.79-84
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5617
Synthesis of 6,7-Disubstituted Pteridine-2,4-diones

Chiara B. Vicentini, Augusto C. Veronese, Mario Guarneri, and Paolo Giori*

*Dipartimento di Scienze Farmaceutiche, Università di Ferrara, via Fossato di Mortara 17, I-44100, Ferrara, Italy


The reaction of pyrimido[5,4-c][1,2,5]oxadiazin-3(5H)-one (1) with carbon nucleophiles afforded pteridine-2,4-diones (3) bearing a variety of substituents unequivocally positioned in the pyrazine ring.