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Paper | Regular issue | Vol 32, No. 5, 1991, pp.937-947
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5688
Reactions of Cyclohexyl and Aryl Pyrazinyl Sulfoxides with Trifluoroacetic Anhydride

Makoto Shimazaki, Miyuki Hikita, Tomoko Hosoda, and Akihiro Ohta*

*Tokyo College of Pharmacy, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

Cyclohexy pyrazinyl sulfoxides reacted with trifluoroacetic anhydride to give 1-cyclohexenyl pyrazinyl sulfides and/or cyclohexyl hydroxypyrazinyl sulfides. The presence of alkyl groups on the pyrazine ring is essential to obtain the latter compounds.