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Paper | Regular issue | Vol 32, No. 7, 1991, pp.1371-1376
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5759
Acid Catalyzed Photoreaction of 5-Chloro-1,3-dimethyluracil with Substituted Benzenes

Kazue Ohkura, Kohki Matsuda, and Koh-ichi Seki*

*Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gukuen University, Ishikari-Tobetsu, Hokkaido 061-0293, Japan

Abstract

The photo-induced substitution of 5-chloro-1,3-dimethyluracil with substituted benzenes, affording the corresponding 5-aryl-1,3-dimethyluracils in appreciable yields, was significantly promoted by the addition of trifluoroacetic acid to the reaction mixture.