Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 32, No. 7, 1991, pp.1387-1390
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5772
Synthesis of 4-(Tributylstannyl)pyridazines by Inverse Electron-demand Diels-Alder Reaction of 1,2,4,5-Tetrazines with Tributylstannylacetylenes

Takao Sakamoto, Nobuyuki Funami, Yoshinori Kondo, and Hiroshi Yamanaka*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

Inverse electron-demand Diels-Alder reaction of 3,6-disubstituted 1,2,4,5-tetrazines with tributylstannylacetylenes containing a substituent gave 4-(tributylstannyl)pyridazines. Particularly, dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate gave 4-(tributylstannyl)pyridazines in good yields. Substitution reaction of 3,6-diphenyl-4-(tributylstannyl)pyridazine was also described.