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Paper | Regular issue | Vol 32, No. 11, 1991, pp.2119-2125
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5811
Synthesis of Conformationnaly Restrained Analogs of 7-n-Butyryl-2,3-dihydro-3-oxo[1,4]benzoxazine, a Normolipemic Pharmacophoric Pattern

Ziaeddine Moussavi, Patrick Depreux, Isabelle Lesieur,* and Jacques Sauzières

*Laboratorie de Chimie Thérapeutique, Faculté de Pharmcie, Université de Lille 2, 3, rue du Professeur Laguesse, BP 83, 59045 Lille Cedex, France

Abstract

Original conformationnaly restrained analogs of 7-n-butyryl-2,3-dihydro-3-oxo[1,4]benzoxazine, a normolipemic pharmacophoric pattern were synthesized from benzoxazinyl or benzoxazolinyl precursors.