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Paper | Regular issue | Vol 34, No. 4, 1992, pp.699-711
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5834
The Synthesis and Spectral Properties of N-(3,4,5-Trimethoxybenzoyl)-3,6-dihydro-1,2-oxazines and N-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,2-oxaziens

Henryk Labaziewicz,* Bob A. Howell, Karl R. Lindfors, and Rodney C. Mason

*Department of Chemistry, Central Michigan University, Mt. Pleasant, MI 48859, U.S.A.


In an attempt to develop neurosedatives of enhanced pharmacological activity and lower side-effect toxicity than those currently available, a series of novel 3,4,5-trimethoxybenzamides derived from either 3,6-dihydro-1,2-oxazine or tetrahydro-1,2-oxazine has been synthesized and fully characterized spectroscopically.