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Communication | Regular issue | Vol 34, No. 1, 1992, pp.5-11
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5857
Additional Bioactive Neolignans from the Roots of Endlicheria dysodantha

Wen-wen Ma, Jon E. Anderson, Jerry L. McLaughlin,* and Karl V. Wood

*Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, U.S.A.

Abstract

Three additional new neolignans, dysodanthins D, E, and F. and one known neolignan, megaphyllone acetate, have been isolated from the ethanol extract of the roots of Endlicheria dysodantha (Lauraceae). Their structures were solved using spectral data. Results of biological testing suggest further evaluation of megaphyllone acetate as an antitumor agent.