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Communication | Regular issue | Vol 34, No. 1, 1992, pp.13-16
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5892
Synthetic Studies on Indole Alkaloids. V. Synthesis of 2-Methyleneindolo[2,3-a]quinolizidines

Anna Diez, David Miguel, Cristina Vila, Mario Rubiralta*, Roland Remuson, and Yvonne Gelas-Mialhe

*Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain


A synthesis of 2-methyleneindolo[2,3-a]quinolizidine (6) by the intramolecular cyclization of N-(2-hydroxyethyl)-2-[1-(phenylsulfonyl)-3-indolyl]-4-methylenepiperidine (9) by the action of t-C4H9OK is reported.