Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 34, No. 1, 1992, pp.111-119
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5898
Synthesis of 2-(Indol-3-yl)methyl-5-methylpyrazines, the Skeleton of Astechrome

Akihiro Ohta,* Hao Jing, Atsushi Maeda, Yasuyo Arai, Mikiko Goto, and Yutaka Aoyagi

*Tokyo College of Pharmacy, 1432-1 Horinouchi, Hachioji, Tokyo 192-03, Japan

Abstract

By the coupling reaction between indolyl-magnesium bromide and 2-tosyloxymethyl-5-methylpyrazines, three 2-(indol-3-yl)-5-methylpyrazines were synthesized. These compounds constitute the skeleton of astechrome, an iron-containing metabolite of Aspergillus terreus IFO 6123 and 8835.