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Paper | Regular issue | Vol 34, No. 1, 1992, pp.121-128
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5901
Synthesis, Glycosidation and Resolution of (±)-Lomatin

Alexios-Léandros Skaltsounis, Sofia Mitaku, Gilbert Gaudel, François Tillequin, and Michel Koch*

*Laboratoire de Pharmacognosie, URA au CNRS n1310, Faculté des Sciences Pharmaceutiques et Biologiques, Université René Descartes, 4 Avenue de l'Observatoire, F-75006 Paris, France


The first resolution of a racemic hydroxydihydropyranocoumarin, (±)-lomatin (1) was achieved by means of glycosidation, followed by separation of the diastereoisomeric glycosides and subsequent acid hydrolysis.