Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 34, No. 2, 1992, pp.363-367
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5933
Synthesis of (2S,4S)-2-Hydroxy-4-hydroxymethyl-4-butanolide, a Hunger Substance

Katsuya Matsumoto,* Takashi Ebata,* Koshi Koseki, Hiroshi Kawakami, Koji Okano, and Hajime Matsushita

*Life Science Research Laboratory, Japan Tobacco Inc., 6-2 Umegaoka, Midori-ku, Yokohama, Kanagawa 227, Japan

Abstract

(2S,4S)-2-Hydroxy-4-hydroxymethyl-4-butanolide (1a), which is a hunger substance, was synthesized stereoselectively starting from D-γ-ribono-1,4-lactone (2).