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Paper | Regular issue | Vol 34, No. 4, 1992, pp.747-756
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5956
A New Synthesis of 7,12-Dihydro-12-phenyl-5H-6,12-methanodibenz[c,f]azocines via N-Benzyl-1,2,3,4-tetrahydro-4-phenylisoquinolin-4-ols

Masaru Kihara,* Minoru Kashimoto, Yoshimaro Kobayashi, and Yoshimitsu Nagao

*Faculty of Pharmaceutical Sciences, The University of Tokushima, Sho-machi, Tokushima 770, Japan

Abstract

7,12-Dihydro-12-phenyl-5H-6,12-methanodibenz[c,f]azocine derivatives were prepared from N-benzyl-1,2,3,4-tetrahydro-4-phenylisoquinolin-4-ols by an intramolecular Friedel-Crafts reaction.