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Communication | Regular issue | Vol 34, No. 4, 1992, pp.643-650
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5963
Synthesis of Chiral 2-Aryl-4-piperidones

Mario Rubiralta,* Anna Diez, Cristina Vila, Josep Castells, and Isabel López

*Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain

Abstract

The synthesis of chiral 2-(2-indolyl)- and 2-(3-indolyl)-4-piperidones by reaction of N,N-dimethyl-4-oxo-2-[1-(phenylsulfonyl)indolyl]piperidinium iodide and (R)-(-)-phenylglycinol is reported.