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Communication | Special issue | Vol 33, No. 1, 1992, pp.121-125
Published online, 1st January, 1970
DOI: 10.3987/COM-91-S41
Synthesis of Na-Methoxyindole and Na-Methoxyoxindole Alkaloids Having Yohimbine Skeleton

Hiromitsu Takayama, Norio Seki, Mariko Kitajima, Norio Aimi, Hiroko Seki, and Shin-ichiro Sakai*

*Faculty of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan

Abstract

Indoloquinolizidine (1) and yohimbine (7) were converted to the corresponding Na-methoxyindoles and Na-methoxyoxindoles by the oxidation of the dihydroindole derivatives with H2O2 and sodium tungstate.