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Paper | Regular issue | Vol 34, No. 11, 1992, pp.2065-2077
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6013
Syntheses of 3,8-Dihydroxyimidazo[1,2-a]pyridines and [1,2-a]pyrazines

Muriel Doise, Dominique Blondeau, and Henri Sliwa*

*Laboratoire de Chimie Organique et Environnement, Université des Sciences et Technologies de Lille, 59655 Villeneuve d’ Ascq Cedex, France

Abstract

3,8-Dihydroxyimidazo[1,2-a]pyridines and [1,2-a]pyrazines were prepared by condensation of glyoxal derivatives with methyl or benzyl ethers of 2-amino-3-hydroxypyridine and pyrazine followed by cleavage of the ether group.