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Paper | Regular issue | Vol 34, No. 7, 1992, pp.1435-1441
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6081
A Facile and Convenient Synthetic Method for 3-Trifluoroacetylpyrroles

Etsuji Okada, Ryoichi Masuda, Masaru Hojo,* and Reiko Yoshida

*Department of Industrial Chemistry, Faculty of Engineering, Kobe University, Kobe 657, Japan

Abstract

3-Trifluoroacetylpyrroles are easily obtained in excellent yields by oxygen-nitrogen exchange reaction of β-trifluoroacetylvinyl ethers with 2,2-dimethoxyethylamie and subsequent cyclodehydration of the products.