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Communication | Regular issue | Vol 36, No. 2, 1993, pp.219-222
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6189
A Convenient Synthesis of 1-Aryl- and 1-Alkyl-1,4,5,6-tetrahydropyridazin-3(2H)-ones

Ki-Jun Hwang* and Kyung-Ho Park

*Korea Research Institute of Chemical Technology, Daeduk-Science Town, Daejoen 305-606, Korea

Abstract

Aryl- and alkylhydrazines react with readily availalbe cyclopropanedicarboxylate (2) in refluxing acetonitrile to afford the corresponding 1-substituted 1,4,5,6-tetrahydropyridazin-3(2H)-ones (5) directly via nitrogen-carbon bond formation, cyclization and decarboxlylation of the cyclized intermediates.