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Communication | Special issue | Vol 35, No. 1, 1993, pp.99-104
Published online, 1st January, 1970
DOI: 10.3987/COM-92-S37
Introduction of Nucleophiles or Ethyl Group to the Indole Nucleus through Nucleophilic Substitution and/or Radical Reactions of 1-Methoxyindole-3- and -2-carboxaldehyde

Fumio Yamada, Yashikazu Fukui, Daisuke Shinmyo, and Masanori Somei*

*Faculty of Pharmaceutical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-0934, Japan

Abstract

1-Methoxyindole-3- and -2-carboxaldehyde were found to undergo nucleophilic substitution and radical reactions resulting in the introduction of nucleophiles and/or ethyl group at the 2- or 3-position.