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■ Synthesis of 1,7,10-Anthyridine Derivatives

Juan Vilar, José M^a Quintela,* Carlos Peinador, Carmen Veiga, and Vicente Ojea

*Departamento de Química Fundamental Industrial, Facultad de Ciencias, Universidad de La Coruña, Campus de A Zapateria, s/n, E-15071, La Coruña, Spain

Abstract

A convenient synthesis of 7-substituted 1,7,10-anthyridin-6(7H)-ones using an enamination ring closure sequence is described. This strategy makes a novel, potencially universal method for the preparation of this new tricyclic ring system.