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Paper | Regular issue | Vol 36, No. 11, 1993, pp.2513-2522
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6475
Synthesis of Pyrroloquinoline and Pyrrolonaphthyridine by an Intramolecular Cyclisation Reaction

Isabelle Cardinaud, Alain Gueiffier,* Jean-Claude Debouzy, Jean-Claude Milhavet, and Jean-Pierre Chapat

*Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS, Faculté de Pharamcie, Université Montpellier I, 15, Avenue Charles Flahault, 34060 Montpellier, France

Abstract

4-Methylthiopyrrolo[1,2-a][1,8]naphthyridine and pyrrolo[1,2-a]quinoline were prepared by an intramolecular cyclisation in acidic media of 1-methylsulfinyl-1-methylthio-2-[3-(2-(1-pyrrolyl)pyridin or phenyl)]ethylene.