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Paper | Regular issue | Vol 38, No. 2, 1994, pp.283-289
Published online, 1st January, 1970
DOI: 10.3987/COM-93-6521
Reaction of 1-Ethoxalylmethylpyrido[2,3-b]pyrazinium Bromide with Ammonium Acetate: Synthesis of Imidazo[1’,2’:1,2]pyrido[5,6-b]pyrazines

Yves Blache,* Alain Gueiffier, Olivier Chavignon, Ahmed Elhakmaoui, Henry Viols, Jean Claude Teulade, Jean Claude Milhavet, Gerard Dauphin, and Jean Pierre Chapat

*Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS, Faculté de Pharamcie, Université Montpellier I, 15, Avenue Charles Flahault, 34060 Montpellier, France


The synthesis of somes imidazo[1’,2’:1,2]pyrido[5,6-b]pyrazines by treatment of quaternary salts of pyrido[2,3-b]pyrazines with ammonium acetate in acetic acid media is described.