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Paper | Regular issue | Vol 38, No. 8, 1994, pp.1813-1822
Published online, 1st January, 1970
DOI: 10.3987/COM-94-6747
A Novel and Convenient Route to (1H-1,2,4-Triazol-1-ylmethyl)phenols, Anilines, N-Alkylanilines and N,N-Dialkylanilines

Alan R. Katritzky,* Saad El-Zemity, and Hengyuan Lang

*Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, P. O. Box 117200, Gainesville, FL 32611-7200, U.S.A.


Phenols, naphthols, anilines, N-alkylanilines and N,N-dialkylanilines are readily alkylated by 1-hydroxymethyl-1,2,4-triazole to afford the corresponding triazole derivatives in good yields.