Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 38, No. 11, 1994, pp.2423-2432
Published online, 1st January, 1970
DOI: 10.3987/COM-94-6858
Molecular Rearrangements in Heterocyclic Synthesis. A Generalized Synthesis of 1,2,4-thiadiazoles from 3-Acylamino-1-oxa-2-azoles

Silvestre Buscemi and Nicolò Vivona*

*Dipartimento di Chimica Organica, Università digli Studi di Palermo, Via Archirafi 20 90123 Palermo, Italy


The sulfuriaztion reaction of some 3-acylamino-1-oxa-2-azoles (1,2,4-oxadiazoles, isoxazoles and 1,2,5-oxadiazoles) with the Lawesson reagent has been investigated. A generalized methodology for the synthesis of 5-aryl-/alkyl-3-substituted 1,2,4-thiadiazoles via molecular rearrangement of the corresponding thioamides has been pointed out.