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Paper | Regular issue | Vol 41, No. 3, 1995, pp.477-485
Published online, 1st January, 1970
DOI: 10.3987/COM-94-6954
Synthesis of 2-(4-Aryl-1E,3E-butadienyl)benzoxazoles by the Horner-Wadsworth-Emmons Reaction

Takatoshi Kosaka and Toshio Wakabayashi*

*Tsukuba Research Institute, Sandoz Pharmaceuticals, LTD., 8 Ohkubo, Tsukuba, Ibaraki 300-33, Japan

Abstract

2-(4-Aryl-1E,3E-butadienyl)benzoxazole derivatives were synthesized by the Horner-Wadsworth-Emmons reaction of 2-phosphorylmethylbenzoxazoles with cinnamaldehydes in fair to good yield.