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Paper | Regular issue | Vol 43, No. 1, 1996, pp.23-32
Published online, 1st January, 1970
DOI: 10.3987/COM-95-7083
Base Catalyzed Condensation Reaction of Malononitrile and 2-Hydroxy-1-naphthaldehyde with Different Ketones

Ahmed A. Fadda, Mohammed T. Zeimaty, Margaret M. Gerges, Hala M. Refat, and Edward R. Biehl*

*Chemistry Department, Southern Methodist University, Dallas, TX 75205, U.S.A.

Abstract

Several derivatives of 2H-phenyl[f]chromene-2-carbonitrile, 2H-benzo[f]chromano[2,3,4:d,e]pyrido[2,3-d]pyrimidine, and benzo[g]-2-quinolone were prepared by the direct condensation of malononitrile with 2-hydroxy-1-naphthaldehyde in the presence of various ketones and ammonium acetate. The effect of solvent, ratio of reactant, and different basic catalysts were studied.