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Paper | Regular issue | Vol 43, No. 5, 1996, pp.953-958
Published online, 1st January, 1970
DOI: 10.3987/COM-95-7319
Simple Synthetic Method of Dialkyl 1,2-Dihydro(iso)quinoline (1 or 2)-Phosphonates

Michiharu Sugiura, Koosuke Asai,* and Yoshiki Hamada

*Faculty of Pharmacy, Meijo University, Yagotoyama, Tempaku-cho, Tempaku-ku, Nagoya 468, Japan

Abstract

1,2-Dihydro(iso)quinoline-2 (or 1)-phosphonates were synthesized from (iso)quinoline, sulfonyl chloride and trialkyl phosphite in CH2Cl2 at room temperature for 1 day in high yields.