Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 42, No. 1, 1996, pp.129-133
Published online, 1st January, 1970
DOI: 10.3987/COM-95-S43
High Pressure Mediated Asymmetric Diels-Alder Reaction of Chiral Sulfinylacrylate Derivatives with Furan and 2-Methoxyfuran

Yoko Nakajima Yamakoshi, Wei-Ying Ge, Jun Sugita, Kazuya Okayama, Tamiko Takahashi, and Toru Koizumi

*Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, Toyama 930-0194, Japan

Abstract

Asymmetric Diels-Alder reaction of chid sulfinylacrylate derivatives (1 and 2) with furan (3) and 2-methoxyfuran (4) proceeded under high pressure (1.2 GPa) conditions to give endo cycloadducts (6c-f). The absolute configuration of adduct (6) was confirmed by conversion of 6e to (-)-COTC (9).