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Paper | Regular issue | Vol 43, No. 8, 1996, pp.1653-1663
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7471
Synthesis of Homohydantoin-Thiazolidine Bicyclic Compounds

Mostafa Hatam, Sabine Köpper, and Jurgen Martens*

*Fachbereich Chemie, Universitat Oldenbrug, P. O. Box 2503 D-26111 Oldenburg, Germany

Abstract

Preparation of various homohydrantoin-thiazolidine bicyclic compounds from 3-thiazolines is described. The reaction of C2-mono-substituted 3-thiazolines proceeds with considerable diastereoselectivity. The assignment for relative configuration of the prepared compounds was carried unequivocally by nmr spectroscopical analysis.