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Communication | Regular issue | Vol 43, No. 11, 1996, pp.2325-2332
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7569
Chimeric Azalides with Functionalized Western Portions

Sherman T. Waddell, Jeffrey M. Eckert, and Timothy A. Blizzard

*Merck Research Laboratories, 50G-231, P.O. Box 2000 Rahway, NJ 07065, U.S.A.

Abstract

A series of chimeric azalides which are homologous to the potent azalide antibiotic 9-deoxo-8a-aza-8a-homoerythromycin A (2) in their easter halves, but which have functionally complex western halves derived from a variety of sources, including carbohydrates, is reported.