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Communication | Regular issue | Vol 43, No. 11, 1996, pp.2357-2360
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7612
A Diastereoselective Synthesis of trans, trans-Octahydronaphthoquinolizine

Hai Mi and David I. Schuster

*Department of Chemistry, New York University, 31 Washington Place, New York, NY 10003, U.S.A.


A facile approach involving stereospecific reduction of an enamine moiety in a tetracyclic system has made it posible to synthesize diastereospecifically the biologically active octahydronaphthoquinolizine with trans, trans stereochemistry.