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Paper | Regular issue | Vol 43, No. 11, 1996, pp.2503-2511
Published online, 1st January, 1970
DOI: 10.3987/COM-96-7615
Reaction of 3-Iodochromone with Nucleophile 1. Reaction of 3-Iodochromone with Azoles

Yoshiaki Sugita and Ichiro Yokoe

*Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japana

Abstract

3-Iodochromone (1a) rected with azoles, such as imidazole and pyrazole to afford 2-(N-azolyl)chromones (2-7) under very mild conditions in high yields. In the case of indoles as the nucleophile, aurone derivatives (9) were obtained together with 2-(N-indolyl)chromones (8).