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Communication | Regular issue | Vol 45, No. 10, 1997, pp.1895-1898
Published online, 1st January, 1970
DOI: 10.3987/COM-97-7926
Formal Synthesis of (-)-Syringolide 1 Starting from D-Xylose Based on a Biomimetic Strategy

Hidemi Yoda,* Miho Kawauchi, Kunihiko Takabe, and Ken Hosoya

*Department of Molecular Science, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku, Hamamatsu 432-8561, Shizuoka, Japan

Abstract

An expeditious and practical synthetic process for a nonproteinaceous elicitor, (-)-syringolide 1, has been developed in a short number of steps utilizing the putative biosynthetic pathway by featuring the elaboration of the protected D-xylose as a starting material.