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Note | Regular issue | Vol 48, No. 1, 1998, pp.181-185
Published online, 1st January, 1970
DOI: 10.3987/COM-97-8004
Synthesis of New 2-Highly Branched 5-Nitroimidazoles by Bis-SRN1 Methodology

Patrice Vanelle,* Kamel Benakli, José Maldonado, and Michel P. Crozet

*Laboratoire de Chimie Organique, Université de la Méditerranée, Faculté de Pharmacie, 27, Boulevard Jean Moulin, 13385 Marseille Cedex 05, France


A versatile bis-SRN1 methodology allows straightforward access to 2-highly branched 5-nitroimidazoles by reacting 3-chloro-2-chloromethyl-1-(1-methyl-5-nitroimidazol-2-yl)prop-1-ene with various nitronate anions.