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Paper | Regular issue | Vol 48, No. 5, 1998, pp.885-891
Published online, 1st January, 1970
DOI: 10.3987/COM-97-8091
A New Indole Alkaloid from Sarcocephalus latifolius

Pedro Abreu* and António Pereira

*Chemistry Department, Faculty of Chemical Technology, New University of Lisbon, Quinta da Torre, 2825 Monte da Caparica, Portugal

Abstract

A new indole alkaloid, 19-O-ethylangustoline, as well as the known alkaloids angustoline, angustine, angustidine and nauclefine were isolated from the stem bark of Sarcocephalus latifolius (Smith) Bruce and characterised by spectral methods. The absolute stereochemistry at C-19 of angustoline and 19-O-ethylangustoline was determined by Horeau’s method and optical rotatory dispersion.