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Communication | Special issue | Vol 47, No. 1, 1998, pp.153-156
Published online, 1st January, 1970
DOI: 10.3987/COM-97-S(N)57
Asymmetric Synthesis of (R)(-)-Dimethyl Citramalate

Sang-sup Jew,* Hyun-ah Kim, Sam-mi Song, Jung-sook Jang, and Hyeung-geun Park

*College of Pharmacy, Seoul National University, Shillim-Dong, San 56-1, Kwanak-Gu, Seoul 151-742, Korea


An asymmetric synthesis of (R)(-)-dimethyl citramalate (1), involving halolactonization by using (S)(-)-proline as a chiral auxiliary, is reported.