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Paper | Special issue | Vol 47, No. 2, 1998, pp.757-763
Published online, 1st January, 1970
DOI: 10.3987/COM-97-S(N)63
Carbocyclic 7-Deazaguanine Oxetanocin Analogues

Jayu Wu, Stewart W. Schneller,* Katherine L. Seley, and Erik De Clercq

*Department of Chemistry, Auburn University, Auburn, AL 36849-5312, U.S.A.

Abstract

The synthesis of two carbocyclic 7-deazaguanosine oxetanocins structurally modified at the C-3’ center and lacking the C-2’ hydroxymethylene group is described. Neither of these target compounds showed antiviral activity against a battery of DNA and RNA viruses.