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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Special issue | Vol 47, No. 2, 1998, pp.655-659
Published online, 1st January, 1970■ A Facile Aldol-Isomerization Route to 3-Alkyldihydropyridinone with a Chiral Azocine Ring
Published online, 1st January, 1970
DOI: 10.3987/COM-97-S(N)88
■ A Facile Aldol-Isomerization Route to 3-Alkyldihydropyridinone with a Chiral Azocine Ring
Yasuhiro Torisawa, Than Soe, Chiaki Katoh, Yumiko Motohashi, Atsushi Nishida, Tohru Hino, and Masako Nakagawa*
*Faculty of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan
Abstract
An efficienf profocol was devised for the synthesis of the chiral dihydropyridinone derivative (19), which involves an aldol-type coupling reaction between N-alkylpiperidin-2-one and Garner aldehyde followed by silane-Rh-mediated olefin isomerization.
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