Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 49, No. 1, 1998, pp.33-37
Published online, 1st January, 1970
DOI: 10.3987/COM-97-S4
An Enantio- and Diastereoselective Synthesis of (-)-Isoretronecanol and (+)-Trachelanthamidine from a meso Precursor

Hiroyuki Konno, Masayo Kishi, Kou Hiroya, and Kunio Ogasawara*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

Two diastereomeric pyrrolizidine alkaloids, (-)-isoretronecanol and (+)-trachelanthamidine, have been synthesized in an enantio- and diastereoselective manner starting from a meso precursor via a catalytic asymmetrization.