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Paper | Regular issue | Vol 48, No. 7, 1998, pp.1423-1430
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8178
Synthesis and Antitumoral Evaluation of 12-Substituted 6,7-Dihydrobenzo[4,5]-cyclohept[1,2-b]indole Derivatives

Benoît Joseph, Virginie Chapellier, Jean-Yves Mérour,* and Stéphane Léonce

*Instiut de Chimie Organique et Analytique, U. F. R. de Sciences, Université d'Orléans, BP 6759, Rue de Chartres, 45067 Orleans Cedex 2, France

Abstract

The synthesis of 12-substituted 6,7-dihydrobenzo[4,5]cyclohept[1,2-b]indole derivatives (2-3) are described. The antiproliferative activity of some of them were evaluated.