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Paper | Regular issue | Vol 48, No. 11, 1998, pp.2287-2308
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8302
Stereocontrolled Synthesis of 1β-Aminoalkylcarbapenems and Tricyclic Carbapenems (Trinems)

Yasuyoshi Iso* and Yasuhiro Nishitani

*Shionogi & Co. Ltd., Discovery research Laboratories, Fukushima-ku, Osaka 553-0002, Japan


The effective synthesis of 1β-aminoalkylcarbapenems and trinems are described and the antibacterial activities of new carbapenem derivatives prepared by this advantageous synthetic method are also reported.